Nervous System Cells: Neurons & Glia
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Nervous System Cells: Neurons & Glia

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Description

Neurons transmit electrochemical signals; glial cells support them. Key neuron types include multipolar, unipolar, and bipolar neurons, while glial cells encompass oligodendrocytes, Schwann cells, astrocytes, microglia, and radial glial cells; nerve impulses involve resting and action potentials, ion pumps, and gated channels.

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Neurons

Cells that receive, sustain, and transmit electrochemical signals throughout the nervous system.

Glial cells

Support cells that outnumber neurons 10:1; enhance signal speed/efficiency, provide nutrient passage, and respond to injury/disease.

Multipolar neuron

Neuron with one axon and multiple dendrites; the most common type.

Multipolar interneuron

Axonless neuron with many dendrites; concentrates neural activity within a single nervous system structure.

Unipolar neuron

Neuron with a single process that branches into dendrite and axon segments.

Bipolar neuron

Neuron with two processes (one dendrite, one axon) extending from the cell body.

Oligodendrocytes

Glial cells that myelinate CNS axons to speed up signal conduction.

Schwann cells

Glial cells that myelinate PNS axons and enable axonal regeneration after damage.

Astrocytes

Star-shaped glial cells that attach to blood vessels and neurons, providing structural/nutritional support.

Microglia

Glial cells that respond to injury/disease by consuming debris and triggering inflammation.

Radial glial cells

Temporary fetal glial network guiding neural migration in the developing neural tube.

Resting potential

Neuron's stable charge (-60 to -80 mV) when not transmitting signals.

Polarized

State of a neuron at resting potential.

Action potential

Brief electrical spike (+50 mV) triggered when membrane potential reaches excitation threshold (-65 mV).

Sodium-potassium pump

Active transporter moving 3 Na+ out and 2 K+ in to maintain ion balance.

Gated ion channels

Channels opening/closing in response to stimuli.

Ligand-gated

Opened by neurotransmitters (e.g., at synapses).

Voltage-gated

Opened by membrane potential changes (e.g., in axons).

Stretch-gated

Activated by mechanical pressure (e.g., in stretch receptors).

Depolarization

Membrane potential increase (e.g., -70 mV → -68 mV) making action potential more likely.

Hyperpolarization

Membrane potential decrease (e.g., -70 mV → -72 mV) inhibiting action potential.

Excitatory postsynaptic potential EPSP

Depolarization from another neuron's firing.

Inhibitory postsynaptic potential IPSP

Hyperpolarization from another neuron's firing.

Summation

Cumulative effect of multiple EPSPs/IPSPs on membrane potential.

All-or-none response

Property where action potentials either fire fully or not at all.